Mefnac Tablet





Mefnac Tablet is an antihypertensive agent. Mefnac Tablet is a prototype drug of Loop Diuretics. Loop diuretics have much greater diuretic effects than thiazides. Mefnac Tablet is a sulfonamide derivative. It has a carboxyl group with a sulfamoyl moiety in the meta position. A halide or phenoxy substitution is present at carbon 4, and a substituted amino group is present at carbon 2 or 3. Mefnac Tablet is characterized by high efficacy and rapid onset of action. It increases the urination and decrease the amount of water retained in the body.


Frusemide or Mefnac Tablet is primarily indicated in conditions like Congestive heart failure, Degradation of pancreatic enzyme suppliments, Edema, Heart failure, Hypertension, Long-term treatment of healed reflux oesophagitis, Oedema, Oliguria, Oliguria due to renal failure, Oliguria due to renal failure, Oliguria due to renal failure, Oliguria due to renal failure, Oliguria due to renal failure, Oliguria due to renal failure, Oliguria due to renal failure, Oliguria due to renal failure, Pulmonary edema, and can also be given in adjunctive therapy as an alternative drug of choice in Bronchopulmonary dysplasia, Hemolytic-uremic syndrome, Hypercalcaemia, Raised intracranial pressure.

Side Effects

The severe or irreversible adverse effects of Frusemide or Mefnac Tablet, which give rise to further complications include Photosensitivity, Skin rashes, Ototoxicity, Nephrocalcinosis, Hyponatremia, Urinary retention, Dizziness, Blurred vision, Hyponatremia, Urinary retention. Frusemide or Mefnac Tablet produces potentially life threatening effects which include Hypokalemia, Cardiac arrhythmias, CHO intolerance, Hypomagnesemia, Hyperosmolar non-ketotic precoma, Hypokalemia, deafness, Hypocalcemic tetany, Ototoxicity, Hypochloremic alkalosis, Life threatening hyponatremia, which are responsible for the discontinuation of Frusemide or Mefnac Tablet therapy. The signs and symptoms that are produced after the acute overdosage of Frusemide or Mefnac Tablet include Postural hypotension, Decreased GFR, Decreased intravascular volume, Sodium & fluid depletion. The symptomatic adverse reactions produced by Frusemide or Mefnac Tablet are more or less tolerable and if they become severe, they can be treated symptomatically, these owsiness, Nausea, Restlessness, Skin rashes, Dry mouth, Hypotension, Muscle cramps, Exfoliative dermatitis, Dry mouth, Skin rashes, thrist.


Frusemide should be used with caution in patients with any pre-existing liver or kidney disease, gout, diabetes, pancreatitis, lupus or allergy to sulfa drugs. This drug is not recommended for use during pregnancy or lactation. Mefnac Tablet causes photosensitization, so use sunscreen and wear protective clothing. Do not use Mefnac Tablet in the late afternoon or evening. Consult with the doctor regarding dosing schedule. Do not porphyric patient.


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