Description

Indications

Metodine DF is primarily indicated in conditions like Acute dental infections, Acute ulcerative gingivitis, Amoebiasis, Anaerobic bacterial infection, Anaerobic infections, Dysentery, Giardiasis, Lung cancer and pancreatic cancer, Pelvic inflammatory disease, Protozoa infection, Schizophrenia and other psychoses, Surgical prophylaxis, Treatment of locally advanced or metastatic pancreatic cancer, Trichomoniasis, Urogenital trichomoniasis, and can also be given in adjunctive therapy as an alternative drug of choice in Amoebic liver abscess, Bacterial vaginosis, Cancer, Clostridium difficile colitis, Crohn’s disease, Dental infections, Helicobacter pylori infection.

Contraindication

Metodine DF is contraindicated in conditions like Alcohol dependence,Blood dyscrasias, Neurosis, Hypersensitivity,Liver damage,Seizures.

Side Effects

The severe or irreversible adverse effects of Metodine DF, which give rise to further complications include Encephalopathy, Convulsions, Ataxia, Peripheral neuropathy, Neutropenia, Seizures, Depression, Headache, Dysarthria, Aseptic meningitis. The signs and symptoms that are produced after the acute overdosage of Metodine DF include Disorientation. The symptomatic adverse reactions produced by Metodine DF are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Dizziness, Vertigo, Headache, Anorexia, Diarrhea, Palpitation, Insomnia, Dry mouth, Maculopapular rash, Rashes, Stomatitis, Urticaria, Pruritus, Dysuria, Gl upset, Flushing, Phlebitis, Nausea and vomiting, Gynecomastia, Chest pain, Metallic taste, Paresthesias, Acute pancreatitis, Darkening of urine, Dry mouth, dizziness, Thrush, Weakness.

Warnings

Metodine DF should be used with caution in patients with any allergy. Avoid use during pregnancy or lactation. Avoid alcoholic beverages while taking this medication as severe stomach upset, nausea, vomiting, headache and flushing can occur.