Description
Indications
Dicloran Topical is primarily indicated in conditions like Acute exacerbation of pain and post operative pain, Acute gout, Ankylosing spondylitis, Bursitis, Gastro-oesophageal reflux disease, Juvenile chronic arthritis, Low back pain, Musculoskeletal disorders, Osteoarthritis, Peptic ulcer, Periarthritis, Pernicious anaemia and other macrocytic anaemias, Post-operative pain, Prevention of postoperative pain, Rheumatoid arthritis, Sprains, Strains, Tendinitis, Tenosynovitis, Tobacco amblyopia and leber’s optic atrophy, Ureteric colic.
Contraindication
Dicloran Topical is contraindicated in conditions like Asthma,Peptic ulcer,Hypersensitivity,GI bleeding, Renal impairment,Hemorrhagic diathesis.
Side Effects
The severe or irreversible adverse effects of Dicloran Topical, which give rise to further complications include Anaphylactoid reactions, Nephrotic syndrome, Blood dyscrasias, Peptic ulceration, Bleeding, Lower gut disorders, Papillary necrosis.Dicloran Topical produces potentially life-threatening effects which include Blood dyscrasias, perforation of peptic ulcer, Anaphylaxis, GI hemorrhage. which are responsible for the discontinuation of Dicloran Topical therapy.The signs and symptoms that are produced after the acute overdosage of Dicloran Topical include Nausea, Vomiting, Melena, Jaundice, Unconsciousness, Dizziness, Headache, Hepatopathy, Oliguria or anuria, Myoclonic encephalopathy, GI hemorrhage, Somnolence, Upper abdominal pain, Hiccup. The symptomatic adverse reactions produced by Dicloran Topical are more or less tolerable and if they become severe, they can be treated symptomatically, these include Flatulence, Dizziness, Vertigo, Tiredness, Headache, Drowsiness, Irritability, Nausea, Vomiting, Anorexia, Diarrhea, Anxiety, Tremors, Abdominal cramps, Constipation, Insomnia, Rashes, Pain, Itching, Burning, Dyspepsia, Depression, Nightmares, Epigastric pain, Taste disturbances, Eye irritation, Paresthesias, Vision disturbances, Hearing disturbances, ulceration of conjuctiva and cornea,.
Warnings
Diclofenac sodium should be used with caution in patients with intrinsic coagulation defects and those on anticoagulant therapy. It should be used with caution in patients with compromised cardiac function, hypertension and other conditions predisposing to fluid retention. It should be used with extra care in the presence of existing uncontrolled infection. Perform periodic auditory (hearing) function test during chronic therapy. Discontinue drug if skin reaction occurs.
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