Description

Overview

Zecef Syrup 125/5ml  is a second generation, semisynthetic cephalosporin antibiotic Cephalosporins are derivatives of 7-aminocephalosporic acid and are closely related to penicillins in structure. Cephalosporins have a six membered sulfur containing ring adjoining a lactam ring Zecef Syrup 125/5ml  is a broad spectrum lactamase resistant antibiotic effective against a wide range of gram positive and gram negative bacteria. Zecef Syrup 125/5ml  (Na) is less effective against gram positive bacterias than first generation drugs. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the medication at regular interval of time throughout the day and night as prescribed. Zecef Syrup 125/5ml  (Na) is important to take the drug for the full time period as prescribed. If you discontinue the therapy, it may result in ineffective treatment

Indications

Zecef Syrup 125/5ml  is primarily indicated in conditions like Acute bronchitis, Bone and joint infection, Chronic bronchitis, Cystitis, Early lyme disease, Genitourinary tract infections, Gonococcal infections, Gonorrhoea, Impetigo, Infected wounds, Latelyme disease prevention, Meningitis, Muscle relaxation (long duration) for surgery and intubation, NSAID-associated gastric or duodenal ulcers, Otitis media, Peritonitis, Pharyngitis, Pneumonia, Post-operative infections, Prophylaxis of acute rejection in allogenic renal transplantation, Pyelonephritis, Respiratory tract infections, Sinusitis, Skin infections, Soft tissue infections, Surgical prophylaxis, Urinary tract infection

Contraindication

Zecef Syrup 125/5ml  is contraindicated in conditions like Hypersensitivity

Side Effects

The severe or irreversible adverse effects of Zecef Syrup 125/5ml , which give rise to further complications include Pseudomembranous colitis, Urticaria, Thrombocytopenia, Hemolytic anemia, Skin rashes, Serum sickness, Hypersensitivity reactions, Drug fever, Thrombophlebitis, Leucopenia, Positive coombs test, Neutropenia, Pruritus Zecef Syrup 125/5ml  produces potentially fe-threatening effects which include Stevens Johnson syndrome, Erythema multiforme, Anaphylaxis, Toxic epidermal necrolysis, which are responsible for the discontinuation of Zecef Syrup 125/5ml  therapy. The signs and symptoms that are produced after the acute overdosage of Zecef Syrup 125/5ml  include Convulsions, Cerebral irritation. The symptomatic adverse reactions produced by Zecef Syrup 125/5ml  are more or less tolerable and if they become severe, they can be treated symptomatically these include Nausea, vomiting, Diarrhea. Urticaria, Pruritus, Jaundice. Skin RashX Pseudomembranous colitis, Elevation of liver enzymes, Drug fever, Gl disturbance, Serum sickness, Erythema multiforme. Epidermal necrolysis, Interstitial nephritis.

Warnings

Zecef Syrup 125/5ml  axetilmay be given to the patient who are hypersensitive to penicillins, although cross-reactions have been reported. Special care is indicated in patients who have experienced penicillin anaphylaxis, prolong use may result in the over growth of non-suseptible organisms Zecef Syrup 125/5ml  should be used with caution in patients with impaired kidney or liver function, hypersensitive to penicillin. Caution is required in early months of pregnancy and in nursing mothers. Appropriate measures should be taken if secondary infection occurs. Reduce dosage when renal function is markedly impaired, High doses should be given with caution along with potent diuretics and aminoglycosides,

High Risk Groups

Drug should not be given to Pregnant Mothers. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies